Loss of sensation or pain due to peripheral neuropathy commonly seen in diabetes is described as which distribution?

• A. Dermatomal distribution
• B. Stocking-glove distribution
• C. Focal distribution
• D. Proximal distribution

Answer: (B)

In diabetic neuropathy the sensory loss tends to be distal and symmetrical, reflecting a length-dependent process that affects the longest nerves first. This creates a stocking-glove pattern: numbness or pain starts in the toes and feet and then involves the hands and fingers in a similar distribution. This reflects a widespread, symmetric polyneuropathy rather than a localized nerve issue.

This pattern helps distinguish it from other distributions. A dermatomal distribution follows a specific nerve root or dorsal root segment and is typical of conditions like herpes zoster. A focal distribution would involve a single nerve in one location, and a proximal distribution would affect areas closer to the body, not the distal extremities.